| 产品详情 |
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| Antigenic Specificity | AXIN1 |
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| Clone | E.882.7 |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 1:50, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | AXIN1 Monoclonal Antibody (E.882.7). This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein), beta 1, 88kDa, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod |
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| Immunogen | n/a |
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| Other Names | axin-1; axis inhibition protein 1; axis inhibitor 1; fused, mouse, homolog of; hAxin |
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| Gene, Accession # | Entrez: 12005, 79257, 8312; Uniprot: O15169, O35625, O70239 |
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| Catalog # | MA5-14790 |
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| Price | |
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| Order / More Info | AXIN1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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