| 产品详情 |
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| Product Name | NVP-BSK805 (hydrochloride) |
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| Description | A potent inhibitor of JAK2 that also inhibits the JAK2V617F mutant enzyme (IC50s for both enzymes ~ 0.5 nM); orally bioavailable with a long half-life in vivo, suppressing leukemic cell spreading and splenomegaly in JAK2V617F cell-driven disease in mice |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | biochemical cancer inhibitor signal transduction kinase protein kinase selective potent JAK2 NVPBSD805 inhibit JAK2V617F V617F mutant enzyme serine threonine tyrosine ATP-competitive ATPcompetitive orally bioavailable long half-life halflife in vivo suppressing suppress leukemic leukemia cell spread splenomegaly disease mice mouse recombinant human erythropoietin-induced polycythemia extramedullary extra medullary erythropoiesis rat |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 16714-1 |
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| Order / More Info | NVP-BSK805 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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