| 产品详情 |
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| Antigenic Specificity | CD15 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG3 |
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| Format | CF-Blue conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The CD15 antigen is expressed on approximately 90% human circulating granulocytes (membranes and granules), 30 to 60% of circulating monocytes and is absent from normal lymphocytes. CD15 antigen is also expressed on Reed Sternberg cells of Hodgkin's disease, on T cell lymphomas including mycosis fungoides and on some leukemias. Outside the hematopoietic system, CD15 expression is described in certain normal and neoplastic epithelial cells and in astrocytes. At least 5 major CD15 antigens (105, 135, 165, 185, 220 kDa) are present on the surface membranes of polymorphonuclear cells. The CD15 antigen is the X-hapten on lacto-N-fucose pentaosyl lll, which is expressed on circulating granulocytes or tissue granulocytes as well as neutrophils and eosinophils. The CD15 antibody recognizes the carbohydrate structure 3-fucosyl-N-acetyl-lactosamine. It specifically labels neutrophils, eosinophils and monoblastoid precursor cells of the myeloid lineage. |
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| Immunogen | X-hapten on lacto-N-fucose pentaosyl lll. |
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| Other Names | CD15 Granulocytes; Cd15; MAB TO CD15; MAB TO CD15 GRANULOCYTES; Lewis X; 3-FAL; 3-FL; LNFP III; Lex; SSEA-1; X-hapten; FUTIV; ELFT; FCT3A; Alpha-(1.3)-fucosyltransferase 4; ELAM-1 ligand fucosyltransferase; Fucosyltransferase 4; Fucosyltransferase IV; Fuc-TIV; FucT-IV; Galactoside 3-L-fucosyltransferase |
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| Gene, Accession # | Gene ID: 2526, SwissProt: P22084 |
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| Catalog # | abx200142 |
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| Price | |
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| Order / More Info | CD15 Antibody from ABBEXA |
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| Product Specific References | n/a |
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