| 产品详情 |
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| Antigenic Specificity | CYP27B1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC, FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CYP27B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha, 25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I. This CYP27B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 482-508 amino acids from the C-terminal region of human CYP27B1. |
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| Immunogen | Human CYP27B1. |
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| Other Names | Cytochrome P450 27B1; CYP27B1; CP2B; CYP1; CYP1alpha; CYP27B; P450c1; PDDR; VDD1; VDDR; VDDRI; VDR; Cytochrome P450 family 27 subfamily B member 1; 25-Hydroxyvitamin D3 1-alpha-hydroxylase; VD3 1A hydroxylase; Cytochrome p450 27B1; 1-alpha-hydroxylase |
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| Gene, Accession # | CYP27B1, Gene ID: 1594, Accession: NP_000776.1, SwissProt: O15528 |
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| Catalog # | abx034211 |
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| Price | |
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| Order / More Info | CYP27B1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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