| 产品详情 |
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| Antigenic Specificity | CYP1B1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CYP1B1 Antibody is a Rabbit Polyclonal antibody against CYP1B1. Cytochrome P450 1B1 (CYP1B1) is a key enzyme involved in the production of potentially carcinogenic estrogen metabolites and the activation of environmental carcinogens and is the predominant member of the CYP1 family expressed in normal breast tissue and breast cancer. Estrogen has been proposed to trigger breast cancer development via an initiating mechanism involving its metabolite, catechol estrogen (CE). CYP1B1 catalyzes the conversion of 17-beta-estradiol to the catechol estrogen metabolites 2-OH-E2 and 4-OH-E2 which have both been postulated to be involved in mammary carcinogenesis. Genetic polymorphisms in CYP1B1 may play an important role in human prostate carcinogenesis as well. Polymorphism of the CYP1B1 gene at codon 432 (Val-->Leu) is associated with a change in catalytic function. |
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| Immunogen | Recombinant protein of human CYP1B1. |
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| Other Names | CP1B; GLC3A; P4501B1; CYP1B1 |
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| Gene, Accession # | CYP1B1, Gene ID: 1545, SwissProt: Q16678 |
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| Catalog # | abx001210 |
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| Price | |
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| Order / More Info | CYP1B1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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| 产品资料 |
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