| 产品详情 |
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| Antigenic Specificity | TCR beta |
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| Clone | H57-597 |
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| Host Species | Armenian Hamster |
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| Reactive Species | mouse |
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| Isotype | IgG |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TCR beta Monoclonal Antibody (H57-597), eBioscience™. The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory autodestructive reactions |
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| Immunogen | n/a |
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| Other Names | TCRbeta, Tib |
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| Gene, Accession # | Entrez: 21577 |
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| Catalog # | 14-5961-81 |
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| Price | |
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| Order / More Info | TCR beta Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 16938836, 17200412, 18773898, 19364921, 19855082, 19933870, 19949102, 19965635, 20061405, 20333242, 20713880, 20935071, 20956344, 21030681, 21129806, 21220453, 21270406, 21347344, 21419664, 21637854, 21659540, 21844383, 21900491, 22190363, 22595758, 22678907, 23272202, 23277487, 23319699, 23601684, 23644504, 23772030, 23988623, 24194936, 24231354, 24244565, 24510964, 24795729, 24924593, 24935457, 24968718, 25012165, 25114101, 25555218, 25599993, 25818301, 25921340, 25956511, 26114424, 26242598, 26404950, 26416167, 26456581, 26479921, 26544571, 26647186, 27045020, 27111144, 27258160, 27528202, 27571405, 27670070, 28008916, 28091533, 28223986, 28382040, 28963568, 29136506, 29249358 |
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