产品详情 |
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Antigenic Specificity | TCR delta |
Clone | TS-1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 200 ug |
Concentration | n/a |
Applications | Flow Cytometry: 1-2 µg/test, Immunohistochemistry (Frozen): Assay Dependent, Immunoprecipitation: Assay Dependent, T-Cell Activation: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCR delta Monoclonal Antibody (TS-1). The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory autodestructive reactions and are believed to be |
Immunogen | n/a |
Other Names | CD3 antigen, delta subunit; CD3d antigen, delta polypeptide (TiT3 complex); OKT3, delta chain; T-cell receptor T3 delta chain; T-cell surface glycoprotein CD3 delta chain, TCRdv1 |
Gene, Accession # | Entrez: 6964 |
Catalog # | TCR1055 |
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Order / More Info | TCR delta Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 10975388, 11292740, 12644316, 16009719, 1978758, 20368575, 2120339, 2142527, 25617367, 26755823, 7511639, 9717967 |
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