| 产品详情 |
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| Antigenic Specificity | LEMD2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:200-1:500, Western Blot: 0.4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LEMD2 Polyclonal Antibody. The LEM (lamina-associated polypeptide-emerin-MAN1) domain is a motif shared by a group of lamin-interacting proteins of the inner nuclear membrane (INM) and nucleoplasm. One such protein, LEMD2 (LEM domain-containing protein 2), is a lamina-associated protein in the INM involved in nuclear structure organization, containing an N-terminal LEM motif, two transmembrane domains, and a MAN1-Src1p C-terminal (MSC) domain. LEMD2 is a truncated paralog of MAN1, lacking the MAN1-specific C-terminal RNA-recognition motif, but like MAN1 is required for myogenic differentiation. Mutations in LEMD2 are thought be among the possible causes of muscle disease. |
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| Immunogen | n/a |
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| Other Names | LEMD2, LEM domain-containing protein 2, LEM2, NET25 |
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| Gene, Accession # | Entrez: 221496, 224640, 361807; Uniprot: Q6DVA0, Q8NC56 |
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| Catalog # | PA5-53589 |
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| Price | |
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| Order / More Info | LEMD2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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