| 产品详情 |
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| Antigenic Specificity | MECR |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:20-1:50, Western Blot: 0.4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MECR Polyclonal Antibody. The mitochondrial trans-2-enoyl-CoA reductase (MECR), was initially identified as nuclear receptor-binding factor 1 (NRBF1), which can interact with a multitude of nuclear hormone receptors in the presence of the respective ligands. MECR has been shown to be part of the mitochondrial fatty acid synthesis (FAS II) system and to catalyze the NAPDH-dependent reduction of 2-enoyl thioesters, generating saturated acyl-groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of genes of FAS II can result in the development of hereditary cardiomyopathy. |
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| Immunogen | n/a |
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| Other Names | MECR;NBRF1; Trans-2-enoyl-CoA reductase, mitochondrial; Trans-2-enoyl-CoA reductase, mitochondrial; Nuclear receptor-binding factor 1 |
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| Gene, Accession # | Entrez: 26922, 51102; Uniprot: Q9BV79, Q9DCS3 |
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| Catalog # | PA5-55967 |
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| Price | |
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| Order / More Info | MECR Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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