产品详情 |
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Antigenic Specificity | CD25 |
Clone | PC61.5.3 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1 |
Format | purified |
Size | 250 ug |
Concentration | n/a |
Applications | Flow Cytometry: 0.5-1 µg/1x10^6 cells, Functional Assay: Assay Dependent, Immunohistochemistry (Frozen): Assay Dependent, Immunoprecipitation: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD25 Monoclonal Antibody (PC61.5.3). CD25 (IL2 receptor alpha chain/IL2RA) is a cytokine that plays a role in the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2RA) is a heterotrimeric protein complex with a gamma chain also shared by interleukin 4 (IL4) and interleukin 7 (IL7). IL2RA, IL2R beta chain (IL2RB), and the IL2R gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric IL2RA chains result in low-affinity receptor, while homodimeric IL2RB chains produce a medium-affinity receptor. The expression of IL2 in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. IL2 is primarily produced by mature T cells. IL2 pl |
Immunogen | n/a |
Other Names | IL2 RA antibody, Il2ra antibody, Interleukin 2 receptor alpha chain antibody, TAC antigen antibody, IL-2R alpha chain |
Gene, Accession # | Entrez: 16184; Uniprot: P01590 |
Catalog # | MA5-17812 |
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Order / More Info | CD25 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 10415029, 11241294, 11342625, 11544316, 11698429, 12538670, 12616481, 12928386, 14645154, 14645588, 15147420, 15528374, 15731228, 16046482, 16177077, 16237077, 16517701, 16709820, 16849462, 17101658, 17159984, 17209058, 17518948, 18390707, 19843942, 20515925, 22927977, 23319295, 26195548, 26347471, 26927797, 27077371, 28006000, 3919312, 3925347, 9040011, 9354659, 9510173, 9723687 |
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