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| Antigenic Specificity | Lyn |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | peptide-ELISA: 1:16000, Western Blot: 0.1-0.3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Lyn Polyclonal Antibody. Lyn (also known as p53/56 Lyn) is a membrane-associated protein tyrosine kinase (PTK) mostly expressed in hemopoietic cells which is important in cellular signaling. It contains an SH2 and SH3 domain and has been found to be cleaved after activation of caspases in apoptosis. A member of the Src family of PTKs, there are two known isoforms for Lyn which plays an indispensable role in the Fc epsilon RI (Fcer1) and the B-cell IgM receptor signaling pathway and is essential for Syk activation and Lat phosphorylation after Fcer1 aggregation and can also phosphor-ylate Tec on multiple residues. Lyn can also be regulated by IL-2 and IL-3.Lyn is a member of the src family of non-receptor protein tyrosine kinases that is pre |
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| Immunogen | n/a |
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| Other Names | LYN ; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog ; FLJ26625 ; JTK8; Yamaguchi sarcoma viral (v-yes-1) related oncogene homolog |
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| Gene, Accession # | Entrez: 4067; Uniprot: P07948 |
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| Catalog # | PA5-18912 |
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| Price | |
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| Order / More Info | Lyn Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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