| 产品详情 |
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| Product Name | HJC0152 (hydrochloride) |
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| Description | An orally bioavailable inhibitor of STAT3 (32 and 62% inhibition at 10 and 20 µM, respectively, in MDA-MB-231 cells in a luciferase reporter assay); inhibits proliferation of MCF-7 and MDA-MB-231 breast cancer and AsPC-1 and PANC-1 pancreatic cancer cells (IC50s = 0.91, 1.64, 1.9, and 1.08 µM, respectively); inhibits tumor growth in a breast cancer mouse xenograft model at doses of 7.5 mg/kg, i.p. or 25 mg/kg, p.o.; inhibits tumor growth in an orthotopic mouse model of squamous cell carcinoma |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1420290-88-5 HJC-0152 STAT-3 MDAMB231 MCF7 AsPC1 PANC1 SCC signal transducer and activator of transcription |
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| Gene, Accession, CAS # | CAS: 1420290-99-8 |
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| Catalog # | 22351-10 |
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| Order / More Info | HJC0152 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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