| 产品详情 |
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| Product Name | ICG-001 |
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| Description | A small molecule inhibitor of β-catenin/cyclic AMP responsive element binding protein binding protein (CBP)-mediated transcription (IC50 = 3 µM); selectively induces apoptosis in transformed colon cells but not in normal cells and prevents the growth of colon carcinoma cells at 25 µM in vitro |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | inhibitors Wnts β-catenins cyclic AMPs responsive elements bindings proteins binding protein CBP transcriptions cancer pulmonary fibrosis cancers stems cells 847591-62-2 868774-16-7 721457-27-8 1402835-92-0 ICG001 ICG 001 antagonists Wnt/β-catenin Wnt/β catenins β TCF-mediated TCF mediated binds element-binding inhibits inhibitions intracellular signaling transductions biochemicals research small molecules cyclic AMP cAMP blocks blocking interactions selectively induces induced apoptosis transformed colon prevents prevention growths carcinomas in vitro disrupts disruptions epithelial-mesenchymal epithelial mesenchymal transitions pulmonary fibrosis regulations regulating |
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| Gene, Accession, CAS # | CAS: 780757-88-2 |
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| Catalog # | 16257-10 |
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| Price | |
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| Order / More Info | ICG-001 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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