产品详情 |
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Antigenic Specificity | TCF3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:1000-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCF3 Polyclonal Antibody. TCF3 (E2A) is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described. |
Immunogen | n/a |
Other Names | bHLHb21, transcription factor 3, TCF-3, E2A, VDIR, ITF1, E47 |
Gene, Accession # | Entrez: 6929; Uniprot: P15923 |
Catalog # | PA5-78190 |
Price | |
Order / More Info | TCF3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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