产品详情 |
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Antigenic Specificity | TCF12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:100-1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCF12 Polyclonal Antibody. TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells. |
Immunogen | n/a |
Other Names | HEB, HTF4, HsT17266, bHLHb20; DNA-binding protein HTF4; E-box-binding protein; TCF-12; class B basic helix-loop-helix protein 20; helix-loop-helix transcription factor 4; transcription factor HTF-4 |
Gene, Accession # | Entrez: 6938; Uniprot: Q99081 |
Catalog # | IHC-00464 |
Price | |
Order / More Info | TCF12 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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