| 产品详情 |
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| Antigenic Specificity | TCF12 |
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| Clone | OTI2E11 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:1000, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TCF12 Monoclonal Antibody (OTI2E11). TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells. |
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| Immunogen | n/a |
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| Other Names | HEB; HTF4; HsT17266; bHLHb20; DNA-binding protein HTF4; E-box-binding protein; TCF-12; class B basic helix-loop-helix protein 20; helix-loop-helix transcription factor 4; transcription factor HTF-4 |
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| Gene, Accession # | Entrez: 6938; Uniprot: Q99081 |
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| Catalog # | MA5-27198 |
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| Price | |
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| Order / More Info | TCF12 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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