产品详情 |
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Product Name | SKL2001 |
Description | An activator of Wnt/β-catenin signaling; increases β-catenin responsive transcription in a cell-based reporter assay in a concentration-dependent manner; increases β-catenin protein levels in HEK293 cells at 10 and 30 µM; disrupts the interaction between Axin and β-catenin; increases ALP activity and mineralization in multipotent mesenchymal ST2 cells, indicating increased osteoblastogenesis; reduces HCT116 and HT-29 spheroid growth and inhibits proliferation of HCT116 and HT-29 cells at 40 µM; induces cell cycle arrest at G0/G1 phase and increases E-cadherin and β-catenin protein levels in HCT116 cells at 40 µM |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Wnt Agonist II |
Gene, Accession, CAS # | CAS: 909089-13-0 |
Catalog # | 26334-25 |
Price | |
Order / More Info | SKL2001 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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