产品详情 |
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Antigenic Specificity | Precerebellin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 10 µg/mL, Western Blot: 2-4 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Precerebellin Polyclonal Antibody. Precerebellin is the precursor of the brain-specific hexadecapeptide cerebellin, a protein with substantial similarity to the globular region of the B chain of complement component C1q. Cerebellin exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/pka- dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release. The active form of precerebellin is highly enriched in postsynaptic structures of cerebellar Purkinje cells in cartwheel neurons of the dorsal cochlear nucleus. Because precerebellin belongs to the C1q/tumor necrosis factor superfamily of secreted |
Immunogen | n/a |
Other Names | cerebellin-1; precerebellin |
Gene, Accession # | Entrez: 12404, 498922, 869; Uniprot: P23435, P63182, Q9R171 |
Catalog # | PA5-20159 |
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Order / More Info | Precerebellin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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