产品详情 |
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Antigenic Specificity | CCR4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | lyophilized |
Applications | Western Blot: 0.5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CCR4 Polyclonal Antibody. CCR4 is a chemokine receptor and is preferentially expressed on type 2 helper T (Th2-type) cells. In contrast to other chemokine receptors, the expression of CCR4 and CCR8 on Th2 cells is transiently increased following TCR and CD28 engagement. Moreover, activated Th1 cells up-regulate CCR4 expression and functional responsiveness to thymus- and activation-regulated chemokine. Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the i |
Immunogen | n/a |
Other Names | C-C chemokine receptor type 4, C-C CKR-4, CC-CKR-4, CCR-4, CCR4, CD194, Ccr4, Cmkbr4 |
Gene, Accession # | Entrez: 12773, 171054; Uniprot: P51680 |
Catalog # | PA5-78948 |
Price | |
Order / More Info | CCR4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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