| 产品详情 |
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| Antigenic Specificity | CCR3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CCR3 Polyclonal Antibody. CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta. CCR3 trasnduces a signal by increasing the intracellular calcium ions level. It also serves as an alternative co-receptor with CD4 for HIV-1 infection. Other chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. |
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| Immunogen | n/a |
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| Other Names | CC-CKR-3, CKR3, CMKBR3, MGC102841 |
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| Gene, Accession # | Entrez: 117027, 1232, 12771; Uniprot: O54814, P51677, P51678 |
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| Catalog # | PA5-19861 |
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| Price | |
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| Order / More Info | CCR3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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