产品详情 |
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Antigenic Specificity | CD45RA |
Clone | MEM-56 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: 1-4 µg/mL, Immunohistochemistry (Paraffin): Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45RA Monoclonal Antibody (MEM-56). CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells. CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing and these isoforms differ in their extracellular domains, however, they share identical transmembrane and cytoplasmic domains. CD45 isoforms differ in their ability to t |
Immunogen | n/a |
Other Names | B220, CD45, CD45R, GP180, LCA, LY5, T200 |
Gene, Accession # | Entrez: 5788; Uniprot: P08575 |
Catalog # | MA1-19113 |
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Order / More Info | CD45RA Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 10220446, 10627531, 10891428, 11120775, 11952818, 12073144, 12388703, 15452178, 16034079, 16378966, 16603627, 16818738, 16888031, 18390743, 18815628, 19180077, 19283780, 19721012, 20104580, 20190192, 20582984, 20592255, 20941600, 21701683, 21908735, 22238455, 22720031, 22824211, 22861368, 23874626, 24788814, 25151500, 25244034, 26053062, 26095669, 26376720, 27087149, 27265873, 9498785, 9792322 |
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