| 产品详情 |
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| Antigenic Specificity | Human CD28 |
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| Clone | CD28.2 |
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| Host Species | Mouse |
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| Reactive Species | human, baboon, capuchin monkey, chimpanzee, cynomolgus, pigtailed macaque, rhesus, sooty mangabey, squirrel monkey |
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| Isotype | IgG1, κ |
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| Format | TotalSeq™-C oligomer conjugate |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | Proteogenomics. TotalSeq™ reagents are designed to profile protein expression at a single cell level following an optimized protocol similar to the CITE-seq workflow. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TotalSeq™-C0386 anti-human CD28. CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation. |
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| Immunogen | n/a |
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| Other Names | T44, Tp44 |
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| Gene, Accession # | Gene ID: 940 |
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| Catalog # | 302963 |
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| Price | |
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| Order / More Info | Human CD28 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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