产品详情 |
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Antigenic Specificity | SPINK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rabbit |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 0.2-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SPINK1 Polyclonal Antibody. This is a trypsin inhibitor, its physiological function is to prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT) [MIM:167800]. A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Defects in SPINK1 are the cause of susceptibility to tropical calcific pancreatitis (TCP) [MIM:608189]. TCP is an idiopathic, juvenile, nonalcoholic form of chronic pancreatitis widely prevalent in several tropical countries. It can be associated with fibrocalculous pancreatic diabetes (FCPD) depending on both environmental and genetic factors. TCP differs from alcoholic pancreatitis by a much |
Immunogen | n/a |
Other Names | Serine peptidase inhibitor, Kazal type 1, PCTT, PSTI, Spink3, TATI, TCP |
Gene, Accession # | Entrez: 103347911, 6690; Uniprot: P00995 |
Catalog # | PA5-40796 |
Price | |
Order / More Info | SPINK1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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