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| Antigenic Specificity | PAR4 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis.It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults.Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration.The tumor suppressor WT1 represses and activates transcription.The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor.Par4 is a WT1 interacting protein that also functions as a transcriptional repressor. |
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| Immunogen | Purified recombinant fragment of PAR4 (aa1-330) expressed in E. coli. |
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| Other Names | coagulation factor II (thrombin) receptor-like 3; coagulation factor II receptor-like 3; F2RL3; PAR-4; protease-activated receptor-4; proteinase-activated receptor 4; thrombin receptor-like 3; PAR4; PAWR |
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| Gene, Accession # | PAWR, Gene ID: 5074, SwissProt: Q96IZ0 |
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| Catalog # | abx016047 |
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| Price | |
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| Order / More Info | PAR4 Antibody from ABBEXA |
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| Product Specific References | n/a |
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