| 产品详情 |
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| Antigenic Specificity | AKT Pan |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Frozen): 1:100-1:500, Immunohistochemistry (Paraffin): 1:100-1:500, Immunoprecipitation: 1:100-1:500, Western Blot: 1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | AKT Pan Polyclonal Antibody. The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. |
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| Immunogen | n/a |
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| Other Names | AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA, AKT1, protein kinase B alpha, rac protein kinase alpha, RAC-alpha serine/threonine-protein kinase, proto-oncogene c-Akt, RAC-PK-alpha, PKB alpha, v-akt murine thymoma viral oncogene homolog 1, PKBB, PKBBETA, PRKBB, RAC-BETA, AKT2, protein kinase B beta, murine thymoma viral (v-akt) homolog-2, protein kinase Akt-2, RAC-PK-beta, PKB beta, rac protein kinase beta, RAC-beta serine/threonine-protein kinase, v-akt murine thymoma viral oncogene homolog 2, DKFZp434N0250, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2, AKT3, PKB gamma, RAC-gamma serine/threonine-protein kinase, RAC-gamma serine/threonine protein kinase, v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) |
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| Gene, Accession # | Entrez: 11651, 207, 24185; Uniprot: P31749, P31750, P47196 |
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| Catalog # | PA5-77855 |
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| Price | |
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| Order / More Info | AKT Pan Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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