| 产品详情 |
| Edit |   |
| Antigenic Specificity | ARHB |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 80 µl, 400 µl |
| Concentration | n/a |
| Applications | WB, IHC. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ARHB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. This ARHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-137 amino acids from the Central region of human ARHB. |
| Immunogen | Human ARHB. |
| Other Names | RHOB; ARH6; ARHB; Rho-related GTP-binding protein RhoB; Rho cDNA clone 6 |
| Gene, Accession # | SwissProt: P62745 |
| Catalog # | abx026689 |
| Price | |
| Order / More Info | ARHB Antibody from ABBEXA |
| Product Specific References | n/a |
| 产品资料 |
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