| 产品详情 |
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| Antigenic Specificity | ASPH |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB, IF/ICC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ASPH Antibody is a Rabbit Polyclonal antibody against ASPH. This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis. |
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| Immunogen | Recombinant protein of human ASPH. |
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| Other Names | AAH; BAH; HAAH; JCTN; FDLAB; junctin; CASQ2BP1; ASPH; Aspartyl/asparaginyl beta-hydroxylase; Aspartate beta-hydroxylase; Peptide-aspartate beta-dioxygenase |
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| Gene, Accession # | ASPH, Gene ID: 444, SwissProt: Q12797 |
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| Catalog # | abx005236 |
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| Price | |
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| Order / More Info | ASPH Antibody from ABBEXA |
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| Product Specific References | n/a |
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