| 产品详情 |
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| Antigenic Specificity | GEF-H1 |
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| Clone | GT336 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:50-1:1000, Immunofluorescence: 1:50-1:1000, Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GEF-H1 Monoclonal Antibody (GT336). GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Alternatively spliced transcript variants encoding different isoforms have been identified. |
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| Immunogen | n/a |
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| Other Names | DKFZp547L106, DKFZp547P1516, FLJ45440, GEF, GEF-H1, GEFH1, KIAA0651, LFP40, P40, ARHGEF2, microtubule-regulated Rho-GEF, Rho/Rac guanine nucleotide exchange factor 2, proliferating cell nucleolar antigen p40, rho guanine nucleotide exchange factor 2, guanine nucleotide exchange factor H1, Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
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| Gene, Accession # | Entrez: 16800, 310635, 9181; Uniprot: Q5FVC2, Q60875, Q92974 |
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| Catalog # | MA5-27803 |
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| Price | |
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| Order / More Info | GEF-H1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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