产品详情 |
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Product Name | Saxagliptin (hydrochloride) |
Description | A potent DPP-4 inhibitor (Ki = 0.6 nM); inhibits DPP-4 ex vivo (ED50 = 0.12 µmol/kg) in plasma from normal fasted rats; reduces plasma glucose levels in Zuckerfa/fa diabetic rats in a dose-dependent manner when administered orally in doses ranging from 0.3-3 mg/kg; increases plasma insulin levels and improves glucose clearance in ob/ob mice; induces systolic and diastolic dysfunction, reduces contractile force, and exacerbates ischemia-reperfusion injury-induced cardiac dysfunction in isolated guinea pig hearts |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | BMS-477118 |
Gene, Accession, CAS # | CAS: 709031-78-7 |
Catalog # | 23697-5 |
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Order / More Info | Saxagliptin (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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