产品详情 |
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Product Name | Phenytoin |
Description | A hydantoin anticonvulsant; inhibits voltage-gated sodium channels in a voltage-dependent manner; suppresses the persistent sodium current in a dose-dependent manner (10-100 µM) in neurons isolated from rat neocortex; reduces seizure frequency and duration by 46 and approximately 20%, respectively, when administered over 7 days (75 mg/kg, i.p., the first day, then 50 mg/kg per day) in a rat model of status epilepticus; oxidized by cytochrome P450 into products that can lead to cell death in vitro and toxic effects in vivo, such as gingival hyperplasia and teratogenicity in rats and mice, respectfully |
Size | 250 g |
Concentration | n/a |
Applications | n/a |
Other Names | 5,5-Diphenylhydantoin|NSC 8722 |
Gene, Accession, CAS # | CAS: 57-41-0 |
Catalog # | 24037-250 |
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Order / More Info | Phenytoin from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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