| 产品详情 |
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| Antigenic Specificity | DSCR1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. The gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of DSCR1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease. This DSCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-252 amino acids from the C-terminal region of human DSCR1. |
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| Immunogen | Human DSCR1. |
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| Other Names | DSCR1; RCAN1; ADAPT78; CSP1; DSC1; Calcipressin-1; Down syndrome critical region protein 1; Myocyte-enriched calcineurin-interacting protein 1; Regulator of calcineurin 1 |
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| Gene, Accession # | Accession: NP_004405.3, NP_981962.1, NP_981963.1, SwissProt: P53805 |
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| Catalog # | abx025111 |
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| Price | |
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| Order / More Info | DSCR1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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