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| Product Name | IACS-010759 |
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| Description | An orally bioavailable inhibitor of mitochondrial complex I; inhibits the ubiquinone reduction activity of isolated murine mitochondrial complex I at 60 nM; reduces basal and spare respiratory capacities and increases glycolytic flux in primary CLL cells at 100 nM; induces apoptosis in CLL cells grown under low glucose conditions or when administered in combination with 2-deoxy-D-glucose; induces tumor regression in a glycolysis-deficient NB1 mouse xenograft model when administered at doses of 5 and 10 mg/kg |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CAS: 1570496-34-2 |
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| Catalog # | 25867-5 |
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| Order / More Info | IACS-010759 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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