| 产品详情 |
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| Antigenic Specificity | Caspase 3 (active/pro) |
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| Clone | 31A1067 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): Assay Dependent, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase 3 (active/pro) Monoclonal Antibody (31A1067). Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into a2b2 tetramer to form the active enzyme. Gene for Caspase 3 also known as Yama, CPP32, and apopain codes for a 32-kDa protein. Caspase 3 cleaves the death substrate poly(ADP-ribose) polymerase (PA |
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| Immunogen | n/a |
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| Other Names | CPP32, CPP32B, SCA-1 |
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| Gene, Accession # | Entrez: 836; Uniprot: P42574 |
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| Catalog # | MA1-91637 |
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| Price | |
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| Order / More Info | Caspase 3 (active/pro) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 27756327 |
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