产品详情 |
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Antigenic Specificity | CHP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CHP2 Polyclonal Antibody. This gene product is a small calcium-binding protein that regulates cell pH by controlling plasma membrane-type Na+/H+ exchange activity. This protein shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway. Another member of the CHP subfamily, Calcineurin B homologous protein 1, is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988). This gene was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinom |
Immunogen | n/a |
Other Names | HCA520 |
Gene, Accession # | Entrez: 308965, 63928, 70261; Uniprot: O43745, Q810D1, Q9D869 |
Catalog # | PA5-39066 |
Price | |
Order / More Info | CHP2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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