产品详情 |
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Antigenic Specificity | CD44v9 |
Clone | RV3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | Alexa Fluor® 594 conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alexa Fluor® 594 anti-human CD44 isoform 9 (CD44v9). CD44 isoform 9, also known as CD44v9, is a CD44 isofom consisting of exons 1-5, 13 (v9) and 15 to 19, product of alternative splicing. CD44v9 is expressed by cancer stem cells, epithelial-type carcinomas, subsets of monocytes and subsets of lymphocytes; have a role in tumor initiation, maintenance and metastasis of cancer cells. CD44v9 interacts with the glutamate-cystine transporter xCT, increasing reduced glutathione and contributing to the ROS resistance of cancer cells, and is a potential predictive marker for recurrence of some cancers and a potential therapeutic target. |
Immunogen | Human CD44v8-10 transfected cells |
Other Names | CD44 variant 9, CD44 variant isoform 9 |
Gene, Accession # | Gene ID: 960 |
Catalog # | 394405 |
Price | |
Order / More Info | CD44v9 Antibody from BIOLEGEND |
Product Specific References | n/a |
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