| 产品详情 |
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| Antigenic Specificity | Mib1/Mindbomb |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC, IF/ICC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MIB is an E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. This protein positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. MIB probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis. This Mib1/Mindbomb antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human Mib1/Mindbomb. |
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| Immunogen | Human Mib1/Mindbomb. |
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| Other Names | MIB1; DIP1; KIAA1323; ZZANK2; E3 ubiquitin-protein ligase MIB1; DAPK-interacting protein 1; Mind bomb homolog 1; Zinc finger ZZ type with ankyrin repeat domain protein 2 |
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| Gene, Accession # | Accession: NP_065825.1, SwissProt: Q86YT6 |
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| Catalog # | abx031563 |
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| Price | |
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| Order / More Info | Mib1/Mindbomb Antibody from ABBEXA |
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| Product Specific References | n/a |
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