| 产品详情 |
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| Antigenic Specificity | RXRA |
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| Clone | K8505 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ChIP assay: Assay Dependent, ELISA: Assay Dependent, Gel Shift: Assay Dependent, Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RXRA Monoclonal Antibody (K8505). Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated lear |
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| Immunogen | n/a |
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| Other Names | NR2B1, nuclear receptor subfamily 2 group B member 1, retinoic acid receptor RXR-alpha, retinoid X nuclear receptor alpha |
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| Gene, Accession # | Entrez: 20181, 25271, 6256; Uniprot: P19793, P28700, Q05343 |
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| Catalog # | 433900 |
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| Price | |
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| Order / More Info | RXRA Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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