产品详情 |
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Antigenic Specificity | Methyl-Histone H3 (Lys18) |
Clone | RM167 |
Host Species | Rabbit |
Reactive Species | human, nonhuman primate |
Isotype | IgG |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: 0.2-1 µg/mL, Peptide Array: 0.1-0.5 µg/mL, Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Methyl-Histone H3 (Lys18) Monoclonal Antibody (RM167). Histone H3 is one of the four core proteins of the nucleosome, and it is involved in transcription regulation, DNA repair, DNA replication and chromosomal stability. The N-terminal tail of Histone H3 undergoes many post-translational modifications, including phosphorylation, acetylation, multiple methylation, ubiquitination, and ADP-ribosylation to achieve its diverse functions. HistoneH3 is acetylated and deacetylated on N-terminal lysine residues. Acetylation removes the positive charge on the histone, decreasing the interaction with the negatively charged phosphate groups of DNA, and resulting in a more relaxed structure associated with greater levels of gene transcription. Acetylati |
Immunogen | n/a |
Other Names | H3 histone family, member A; H3a; H3K9ac; HIST1H3A; Histone 1; histone 1, H3a; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l |
Gene, Accession # | Entrez: 8350; Uniprot: P68431 |
Catalog # | MA5-24681 |
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Order / More Info | Methyl-Histone H3 (Lys18) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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