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| Product Name | AMD 3465 (hydrobromide) |
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| Description | Blocks the cell surface binding of the CXCR4 ligand CXCL12 (IC50 = 18 nM), inhibits calcium mobilization (IC50 = 4 nM), and (at 6,250 nM) completely blocks chemotaxis of SupT1 cells; active against various HIV strains (IC50s = 6-12 nM) |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | receptors antagonist infectious diseases immunlogy cancers HIV CXCR4 CXCL12 chemokind ligands antagoinst chemotaxis T-cells activation immunology AMD3465 AMD-3465 C-X-C chemokine receptors CXCR-4 CXCL-12 blocks binds inhibits inhibitions inhibitors calcium mobilization SupT1 HIC eosinophil granuloma formations Tcell T cells lymphoid tissues tumor growth cAMP xenograft models medulloblastoma glioblastoma 185991-24-6 |
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| Gene, Accession, CAS # | CAS: 185991-07-5 |
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| Catalog # | 11959-5 |
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| Order / More Info | AMD 3465 (hydrobromide) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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