产品详情 |
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Antigenic Specificity | GPR56 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | ELISA: 1:20,000, Immunocytochemistry: 1:200-1:1000, Immunofluorescence: 1:200-1:1000, Western Blot: 1:500-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GPR56 Polyclonal Antibody. Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination (PubMed:21768377). Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche (PubMed:23478665). Plays a critical role in tumourigenesis. Plays essential role in testis development (Pu |
Immunogen | n/a |
Other Names | BFPP, DKFZp781L1398, TM7LN4, TM7XN1 |
Gene, Accession # | Entrez: 9289; Uniprot: Q9Y653 |
Catalog # | PA5-50979 |
Price | |
Order / More Info | GPR56 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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