| 产品详情 |
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| Antigenic Specificity | Clathrin Heavy Chain |
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| Clone | BF-06 |
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| Host Species | Mouse |
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| Reactive Species | bovine, human, mouse, porcine, rat |
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| Isotype | IgM |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Flow Cytometry: 2-5 µg/mL, Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Clathrin Heavy Chain Monoclonal Antibody (BF-06). Clathrin is a submembrane protein that polymerizes into coat-like lattices, which results in membrane invagination. The basic oligomers are composed of three clathrin heavy chain (180 kDa) and three light chain (30 kDa) subunits and the process of polymerization is dynamically regulated by the light chains. Interaction of clathrin with the plasma membrane is mediated by adaptor proteins (AP1-4) specific for different cellular compartments. Another proteins, such as endophilin, epsin and amphiphysin are involved in membrane invagination and clathrin rearrangements. Finally, dynamin functions at the fission stage of clathrin-mediated endocytosis. |
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| Immunogen | n/a |
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| Other Names | CHC, CHC17, CLH-17, CLTCL2, Hc, KIAA0034, clathrin heavy chain 1, clathrin heavy chain on chromosome 17, clathrin, heavy polypeptide (Hc), clathrin, heavy polypeptide-like 2 |
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| Gene, Accession # | Entrez: 100271929, 1213, 281080, 54241, 67300; Uniprot: P11442, P49951, Q00610, Q68FD5 |
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| Catalog # | MA1-10316 |
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| Price | |
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| Order / More Info | Clathrin Heavy Chain Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 25662767 |
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