产品详情 |
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Antigenic Specificity | CD43 |
Clone | W3/13HLK |
Host Species | Mouse |
Reactive Species | rat |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 50 ug |
Concentration | n/a |
Applications | Flow Cytometry: 0.5 µg/1x10^6 cells |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD43 Monoclonal Antibody (W3/13HLK), PE. CD43 (leukosialin, sialophorin) is a transmembrane mucin-like protein with high negative charge, expressed on the surface of most hematopoietic cells. CD43 contributes to a repulsive barrier that interferes with cellular adhesion, however, in certain cases also promotes leukocyte aggregation. By interaction with actin-binding proteins ezrin and moesin CD43 plays a regulatory role in remodeling T-cell morphology and regulates cell-cell interactions during lymphocyte traffic. CD43 signaling both enhances LFA-1 adhesiveness and counteracts LFA-1 induction via other receptors. Expression of CD43 causes induction of functionally active tumor suppressor p53 protein, but in case of p53 and ARF deficiency CD |
Immunogen | n/a |
Other Names | CD43, GALGP, GPL115, LSN, galactoglycoprotein, leukocyte sialoglycoprotein, leukosialin, sialophorin gpL115, leukosialin, CD43 |
Gene, Accession # | Entrez: 24796; Uniprot: P13838 |
Catalog # | MA5-17386 |
Price | |
Order / More Info | CD43 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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