产品名称 CD43 Antibody from INVITROGEN ANTIBODIES
产品货号 MA5-16339
产品价格 现货询价,电话:010-67529703
产品规格 500 µL
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityCD43
CloneSP55
Host SpeciesRabbit
Reactive Specieshuman
IsotypeIgG
Formatpurified
Size500 µL
Concentrationn/a
ApplicationsFlow Cytometry: 1:100, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:25
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DescriptionCD43 Monoclonal Antibody (SP55). CD43 (leukosialin, sialophorin) is a transmembrane mucin-like protein with high negative charge, expressed on the surface of most hematopoietic cells. CD43 contributes to a repulsive barrier that interferes with cellular adhesion, however, in certain cases also promotes leukocyte aggregation. By interaction with actin-binding proteins ezrin and moesin CD43 plays a regulatory role in remodeling T-cell morphology and regulates cell-cell interactions during lymphocyte traffic. CD43 signaling both enhances LFA-1 adhesiveness and counteracts LFA-1 induction via other receptors. Expression of CD43 causes induction of functionally active tumor suppressor p53 protein, but in case of p53 and ARF deficiency CD43 promo
Immunogenn/a
Other NamesCD43, GALGP, GPL115, LSN, galactoglycoprotein, leukocyte sialoglycoprotein, leukosialin, sialophorin gpL115, leukosialin, CD43
Gene, Accession #Entrez: 6693; Uniprot: P16150
Catalog #MA5-16339
Price
Order / More InfoCD43 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料