| 产品详情 |
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| Antigenic Specificity | Amphiregulin |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 10 µg/mL, Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Amphiregulin Polyclonal Antibody. Amphiregulin (AR) binds to EGF-Receptor (EGFR) with lower affinity than EGF. The mature secreted form AR is an 84-amino acid residue glycosylated polypeptide growth regulator, which is generated by proteolytic processing of a 252-amino acid transmembrane precursor. Seven different polypeptide ligands, which derive from distinct genes, are capable of binding to the extracellular domain of EGFR. These ligands include EGF, TGFalpha, AR, HB-EGF, cripto-1, epiregulin, and betacellulin. All of these growth factors contain a characteristic EGF-like domain which is defined by 6 evenly spaced cysteine residues that generate 3 loops through the formation of disulfide bonds. AR protein has been localized by immunohist |
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| Immunogen | n/a |
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| Other Names | colorectum cell-derived growth factor, schwannoma-derived growth factor |
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| Gene, Accession # | Entrez: 11839, 374; Uniprot: P15514, P31955 |
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| Catalog # | PA5-16621 |
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| Price | |
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| Order / More Info | Amphiregulin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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