产品详情 |
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Antigenic Specificity | Amphiregulin |
Clone | AREG559 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | phycoerythrin (PE) conjugate |
Size | 100 Tests |
Concentration | n/a |
Applications | Flow Cytometry: 5 µL (0.25 µg)/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Amphiregulin Monoclonal Antibody (AREG559), PE, eBioscience™. Amphiregulin (AR) binds to EGF-Receptor (EGFR) with lower affinity than EGF. The mature secreted form AR is an 84-amino acid residue glycosylated polypeptide growth regulator, which is generated by proteolytic processing of a 252-amino acid transmembrane precursor. Seven different polypeptide ligands, which derive from distinct genes, are capable of binding to the extracellular domain of EGFR. These ligands include EGF, TGFalpha, AR, HB-EGF, cripto-1, epiregulin, and betacellulin. All of these growth factors contain a characteristic EGF-like domain which is defined by 6 evenly spaced cysteine residues that generate 3 loops through the formation of disulfide bonds. AR protei |
Immunogen | n/a |
Other Names | Amphiregulin; amphiregulin B; AR; Colorectum cell-derived growth factor; CRDGF; Schwannoma-derived growth factor; SDGF |
Gene, Accession # | Entrez: 374; Uniprot: P15514 |
Catalog # | 12-5370-42 |
Price | |
Order / More Info | Amphiregulin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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