| 产品详情 |
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| Antigenic Specificity | Amphiregulin |
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| Clone | AREG559 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay-Dependent, Western Blot: 1-10 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Amphiregulin Monoclonal Antibody (AREG559), eBioscience™. Amphiregulin (AR) binds to EGF-Receptor (EGFR) with lower affinity than EGF. The mature secreted form AR is an 84-amino acid residue glycosylated polypeptide growth regulator, which is generated by proteolytic processing of a 252-amino acid transmembrane precursor. Seven different polypeptide ligands, which derive from distinct genes, are capable of binding to the extracellular domain of EGFR. These ligands include EGF, TGFalpha, AR, HB-EGF, cripto-1, epiregulin, and beta cellulin. All of these growth factors contain a characteristic EGF-like domain which is defined by six evenly spaced cysteine residues that generate three loops through the formation of disulfide bonds. AR pro |
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| Immunogen | n/a |
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| Other Names | Colorectum cell-derived growth factor, CRDGF, AREG, SDGF, Mcub, AREGB, MGC13647 |
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| Gene, Accession # | Entrez: 374; Uniprot: P15514 |
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| Catalog # | 14-5370-82 |
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| Price | |
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| Order / More Info | Amphiregulin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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