产品详情 |
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Antigenic Specificity | CD45 |
Clone | HI30 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Alexa Fluor 405 conjugate |
Size | 500 µL |
Concentration | n/a |
Applications | Flow Cytometry: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45 Monoclonal Antibody (HI30), Alexa Fluor 405. CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains. CD45RA is an isoform of the CD45 complex and has restricted expression b |
Immunogen | n/a |
Other Names | B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, CD45 antigen, T200 glycoprotein, T200 leukocyte common antigen, protein tyrosine phosphatase, receptor type, c polypeptide, receptor-type tyrosine-protein phosphatase C |
Gene, Accession # | Entrez: 5788; Uniprot: P08575 |
Catalog # | MHCD4526 |
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Order / More Info | CD45 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 20976265, 26080707 |
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