产品详情 |
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Antigenic Specificity | CD45 |
Clone | 30-F11 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b, kappa |
Format | PE-Cyanine7 conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.125 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45 Monoclonal Antibody (30-F11), PE-Cyanine7, eBioscience™. CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains. CD45RA is an isoform of the CD45 complex and has restr |
Immunogen | n/a |
Other Names | Cluster designation 45, common leukocyte antigen, T220 and B220 |
Gene, Accession # | Entrez: 19264; Uniprot: P06800 |
Catalog # | 25-0451-82 |
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Order / More Info | CD45 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 19139167, 19786532, 21220692, 21389872, 21421850, 21703864, 21989919, 22628281, 22686371, 22887839, 22905869, 23148236, 23185234, 23284862, 23459632, 23604318, 23766529, 23922928, 23947835, 23969310, 24366868, 24401681, 24446236, 24567448, 24624965, 24625684, 24657994, 24690491, 24733756, 24763809, 24942009, 25030167, 25236433, 25445147, 25474413, 25474593, 25575749, 25637383, 25658639, 25664855, 25693182, 25858253, 26030851, 26047815, 26074812, 26107883, 26170908, 26206316, 26257993, 26277898, 26344905, 26438363, 26503169, 26572749, 26582949, 26611836, 26617239, 26635184, 26656646, 26779981, 26797765, 26854397, 26964571, 26999600, 27027096, 27057467, 27068890, 27224029, 27335895, 27348591, 27453007, 27494521, 27538380, 27577867, 27659202, 27736987, 27860312, 27886180, 28000790, 28134623, 28218906, 28225153, 28273719, 28298295, 28332979, 28405519, 28467822, 28485322, 28494939, 28507796, 28521131, 28594896, 28716934, 28758901, 28814662, 28819169, 29162901, 29187227, 29230039, 29296539, 29449644, 29500407 |
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