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Antigenic Specificity | CD45 |
Clone | 30-F11 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b, kappa |
Format | phycoerythrin (PE) conjugate |
Size | 50 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.125 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45 Monoclonal Antibody (30-F11), PE, eBioscience™. CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains. CD45RA is an isoform of the CD45 complex and has restricted exp |
Immunogen | n/a |
Other Names | Cluster designation 45, common leukocyte antigen, T220 and B220 |
Gene, Accession # | Entrez: 19264; Uniprot: P06800 |
Catalog # | 12-0451-81 |
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Order / More Info | CD45 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 15833919, 16597594, 18634851, 19451396, 19497969, 21393582, 21421850, 21703864, 21907166, 21925233, 21989919, 22031549, 22577135, 22628281, 22686371, 22722868, 23159881, 23180724, 23232367, 23354167, 23520544, 23776077, 23804447, 23812634, 23867620, 24336287, 24366868, 24401681, 24446236, 24465914, 24624965, 24627421, 24662049, 24733756, 24875883, 24983456, 25198549, 25313857, 25368192, 25445147, 25471571, 25538248, 25648335, 25658639, 25664855, 25693182, 25840412, 25858253, 25985364, 26030851, 26047815, 26107883, 26170908, 26257993, 26277898, 26344905, 26401006, 26531897, 26572749, 26573799, 26617239, 26656646, 26699479, 26779981, 26809474, 26854397, 26935695, 27057467, 27068890, 27158674, 27335895, 27385780, 27538380, 27577867, 27659202, 27860312, 27869129, 27889319, 28000790, 28134623, 28165063, 28218906, 28273719, 28330582, 28332979, 28485322, 28494939, 28594896, 28716934, 28768912, 28814662, 28924369, 29018045, 29030607, 29162901, 29187227, 29371665, 29500407, 29515165, 29723263 |
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