| 产品详情 |
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| Antigenic Specificity | CD2AP |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:50-1:200, Western Blot: 0.4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD2AP Polyclonal Antibody. This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. |
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| Immunogen | n/a |
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| Other Names | CMS, Cas ligand with multiple Src homology 3 SH3 domains, adapter protein CMS, cas ligand with multiple SH3 domains |
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| Gene, Accession # | Entrez: 12488, 23607, 316258; Uniprot: F1LRS8, Q9JLQ0, Q9Y5K6 |
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| Catalog # | PA5-51879 |
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| Price | |
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| Order / More Info | CD2AP Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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